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KMID : 1130620110070040227
Journal of Clinical Neurology
2011 Volume.7 No. 4 p.227 ~ p.230
Pure Word Deafness in a Patient with Early-Onset Alzheimer¡¯s Disease: An Unusual Presentation
Kim Sook-Hui

Suh Mee-Kyung
Seo Sang-Won
Chin Ju-Hee
Han Seol-Heui
Na Duk-Lyul
Abstract
Background and Purpose: The occurrence of PWD in neurodegenerative disease is very rare, and this is the first report of it being related to early-onset AD. We describe a patient with early-onset Alzheimer¡¯s disease (AD) who presented with pure word deafness (PWD).

Case Report: The patient had experienced PWD for 2 years, followed by other cognitive deficits suggestive of parietotemporal dysfunction. Brain imaging including 18FDG-PET and [11C] PIB-PET supported the diagnosis of AD.
Conclusions: Our case highlights the clinical variability that characterizes early-onset AD.
KEYWORD
pure word deafness, Alzheimer¡¯s disease, primary progressive aphasia
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